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Background: The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. Applications: ELISA, IHC Name of antibody: GTF3A Immunogen: Synthetic peptide of human GTF3A Full name: general transcription factor IIIA Synonyms: AP2; TFIIIA SwissProt: Q92664 ELISA Recommended dilution: 5000-10000 IHC positive control: Human tonsil IHC Recommend dilution: 50-300
Background:
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.
Applications:
ELISA, IHC
Name of antibody:
GTF3A
Immunogen:
Synthetic peptide of human GTF3A
Full name:
general transcription factor IIIA
Synonyms:
AP2; TFIIIA
SwissProt:
Q92664
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human tonsil
IHC Recommend dilution:
50-300