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  • 產(chǎn)品名稱:兔抗TNFRSF1B多克隆抗體

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中文名稱:兔抗TNFRSF1B多克隆抗體   

英文名稱: Anti-TNFRSF1B rabbit polyclonal antibody

別      名: p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II

抗      原: TNFRSF1B

儲(chǔ)      存: 冷凍(-20℃)

宿      主: Rabbit

相關(guān)類別: 一抗

反應(yīng)種屬: Human

標(biāo) 記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.

Applications:

ELISA, WB, IHC

Name of antibody:

TNFRSF1B

Immunogen:

Fusion protein of human TNFRSF1B

Full name:

Tumor necrosis factor receptor superfamily, member 1B

Synonyms:

p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II

SwissProt:

P20333

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human liver cancer and human cervical cancer

IHC Recommend dilution:

5-20

WB Predicted band size:

48 kDa

WB Positive control:

Human colon cancer

WB Recommended dilution:

200-1000





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